{"ok":true,"trend":{"id":93360,"platform":"news","region":"global","key":"rational selection of spcas9 and variant-derived adenine base editors for human genome editing","title":"Rational selection of SpCas9 and variant-derived adenine base editors for human genome editing","url":"https://news.google.com/rss/articles/CBMiX0FVX3lxTE9McFhhTnVuT1MwVEZ5ZUJoWlNEVVJoV2dMNjBRMnR5aC1ndnk3bjkzM2RBN0VnQlIzYktrUEZRcmtfaGt1em4wRmJQWVo0V0FVUWhLcXczVFNQLTduUUs4?oc=5","first_seen":"2026-09-27T09:47:45.798635Z","last_seen":"2026-09-27T12:31:45.644279Z","last_rank":37,"peak_rank":37,"last_volume":null,"peak_volume":0,"seen_count":3,"score":20.53,"category_hint":"biology","section":"science","category":"biology","summary":"A study published in Nature presents a rational framework for choosing between SpCas9 and variant-derived adenine base editors when editing the human genome. The work helps researchers match editor choice to specific target sites, improving precision and efficiency of base-editing experiments and supporting safer therapeutic applications.","why":"Base editing is a fast-moving area of genome medicine, and practical guidance on editor selection is of wide interest to researchers developing therapies.","tone":"neutral","entities":["SpCas9","adenine base editors","Nature"],"summarized_at":"2026-09-27T09:48:44.607800Z","meta":{"via":"scan","lang":"en","term":"genome","source":"Nature","generic":0.1,"published":"Sun, 27 Sep 2026 07:14:58 GMT"},"nw":0.39,"promo":0.01,"kind":"news_event","importance":1.57,"hidden":false,"hide_reason":null,"judged_at":"2026-09-27T09:47:46.132689Z","title_en":"New guidance for selecting adenine base editors in human genome editing","section_name":"Science","category_name":"Biology","timeline":[{"captured_at":"2026-09-27T09:47:45.798635Z","rank":37,"volume":null},{"captured_at":"2026-09-27T11:09:45.610982Z","rank":37,"volume":null},{"captured_at":"2026-09-27T12:31:45.644279Z","rank":37,"volume":null}],"posts":[{"platform":"news","url":"https://news.google.com/rss/articles/CBMiX0FVX3lxTE9McFhhTnVuT1MwVEZ5ZUJoWlNEVVJoV2dMNjBRMnR5aC1ndnk3bjkzM2RBN0VnQlIzYktrUEZRcmtfaGt1em4wRmJQWVo0V0FVUWhLcXczVFNQLTduUUs4?oc=5","author":"Nature","title":"Rational selection of SpCas9 and variant-derived adenine base editors for human genome editing","snippet":null,"posted_at":"2026-09-27T07:14:58Z","likes":null}],"elsewhere":[],"window":"7d"}}