{"ok":true,"trend":{"id":771775,"platform":"hn","region":"global","key":"scientists untangle the biology of an 'undruggable' cancer gene","title":"Scientists untangle the biology of an 'undruggable' cancer gene","url":"https://www.nytimes.com/2026/10/02/science/scientists-untangle-the-biology-of-an-undruggable-cancer-gene.html","first_seen":"2026-10-02T19:50:39.626532Z","last_seen":"2026-10-06T10:16:52.128478Z","last_rank":12,"peak_rank":2,"last_volume":11,"peak_volume":11,"seen_count":24,"score":66.73,"category_hint":"biology","section":"science","category":"biology","summary":"Researchers have mapped the biology of a cancer gene long considered 'undruggable', opening a possible path to targeted therapies against one of oncology's most stubborn targets. The New York Times reports on the advance, which is drawing attention as a meaningful step in cancer research, with readers debating how soon the basic-science insight could translate into actual treatments.","why":"A breakthrough against a notoriously difficult cancer target is notable news for anyone following medicine and drug development.","tone":"positive","entities":["New York Times","cancer researchers"],"summarized_at":"2026-10-06T11:25:37.021422Z","meta":{"via":"scan","lang":"en","link":"https://www.nytimes.com/2026/10/02/science/scientists-untangle-the-biology-of-an-undruggable-cancer-gene.html","term":"biology","hn_id":"49937193","comments":5},"nw":null,"promo":null,"kind":null,"importance":null,"hidden":false,"hide_reason":null,"judged_at":null,"title_en":"Scientists untangle the biology of an 'undruggable' cancer gene","section_name":"Science","category_name":"Biology","timeline":[{"captured_at":"2026-10-02T19:50:39.626532Z","rank":28,"volume":6},{"captured_at":"2026-10-02T22:38:26.660671Z","rank":12,"volume":9},{"captured_at":"2026-10-03T00:01:16.963269Z","rank":5,"volume":9},{"captured_at":"2026-10-03T04:08:23.535815Z","rank":12,"volume":10},{"captured_at":"2026-10-03T05:30:27.286602Z","rank":12,"volume":10},{"captured_at":"2026-10-03T10:59:51.841303Z","rank":12,"volume":10},{"captured_at":"2026-10-03T17:50:15.386687Z","rank":12,"volume":11},{"captured_at":"2026-10-03T19:12:15.755434Z","rank":12,"volume":11},{"captured_at":"2026-10-03T20:35:19.392873Z","rank":12,"volume":11},{"captured_at":"2026-10-03T23:20:14.841482Z","rank":8,"volume":11},{"captured_at":"2026-10-04T00:42:49.632430Z","rank":11,"volume":11},{"captured_at":"2026-10-04T02:05:29.886077Z","rank":12,"volume":11},{"captured_at":"2026-10-04T03:27:29.965133Z","rank":12,"volume":11},{"captured_at":"2026-10-04T08:56:53.714689Z","rank":12,"volume":11},{"captured_at":"2026-10-05T00:01:35.760722Z","rank":4,"volume":11},{"captured_at":"2026-10-05T02:45:46.940597Z","rank":12,"volume":11},{"captured_at":"2026-10-05T05:30:26.859301Z","rank":2,"volume":11},{"captured_at":"2026-10-05T09:36:47.934515Z","rank":12,"volume":11},{"captured_at":"2026-10-05T12:21:09.602236Z","rank":12,"volume":11},{"captured_at":"2026-10-05T23:18:31.150493Z","rank":10,"volume":11},{"captured_at":"2026-10-06T00:40:31.681771Z","rank":12,"volume":11},{"captured_at":"2026-10-06T02:03:11.850747Z","rank":9,"volume":11},{"captured_at":"2026-10-06T03:25:11.509683Z","rank":12,"volume":11},{"captured_at":"2026-10-06T10:16:52.128478Z","rank":12,"volume":11}],"posts":[{"platform":"hn","url":"https://news.ycombinator.com/item?id=49937193","author":"gumby","title":"Scientists untangle the biology of an 'undruggable' cancer gene","snippet":null,"posted_at":"2026-10-02T18:58:31Z","likes":11}],"elsewhere":[],"window":"7d"}}