{"ok":true,"trend":{"id":515240,"platform":"mastodon","region":"global","key":"clues to why a breakthrough pancreatic cancer drug eventually stops working https://www.nytimes.com/2026/09/30/science/p","title":"Clues to Why a Breakthrough Pancreatic Cancer Drug Eventually Stops Working https://www.nytimes.com/2026/09/30/science/p","url":"https://www.nytimes.com/2026/09/30/science/pancreatic-cancer-drug-daraxonrasib-ben-sasse-resistance.html","first_seen":"2026-09-30T18:39:46.872541Z","last_seen":"2026-10-01T05:37:48.649158Z","last_rank":6,"peak_rank":1,"last_volume":2,"peak_volume":3,"seen_count":9,"score":75.06,"category_hint":"medicine","section":"health","category":"health","summary":"New reporting examines why daraxonrasib, a breakthrough drug for pancreatic cancer, eventually stops working in patients. Researchers have identified clues about the resistance mechanisms that develop over time, a step that could guide combination treatments and extend the drug's effectiveness for one of the deadliest cancers.","why":"Fresh research on drug resistance in a promising pancreatic cancer treatment has drawn attention from clinicians, patients and science readers.","tone":"neutral","entities":["daraxonrasib","pancreatic cancer","New York Times"],"summarized_at":"2026-10-01T00:43:36.367816Z","meta":{"tag":"medicine","via":"scan","kind":"status","lang":"en","instance":"mastodon.social","tag_uses":38},"nw":null,"promo":null,"kind":null,"importance":null,"hidden":false,"hide_reason":null,"judged_at":null,"title_en":"Clues Emerge on Why Pancreatic Cancer Drug Stops Working","section_name":"Health","category_name":"Health","timeline":[{"captured_at":"2026-09-30T18:39:46.872541Z","rank":2,"volume":3},{"captured_at":"2026-09-30T18:39:46.872541Z","rank":5,"volume":2},{"captured_at":"2026-09-30T18:39:46.872541Z","rank":6,"volume":2},{"captured_at":"2026-09-30T18:40:49.326566Z","rank":1,"volume":3},{"captured_at":"2026-09-30T18:40:49.326566Z","rank":2,"volume":2},{"captured_at":"2026-09-30T20:01:48.418866Z","rank":5,"volume":3},{"captured_at":"2026-09-30T20:02:48.141580Z","rank":1,"volume":3},{"captured_at":"2026-09-30T20:02:48.141580Z","rank":2,"volume":2},{"captured_at":"2026-09-30T21:25:08.220297Z","rank":2,"volume":3},{"captured_at":"2026-09-30T21:25:08.220297Z","rank":4,"volume":2},{"captured_at":"2026-09-30T22:47:08.833539Z","rank":5,"volume":2},{"captured_at":"2026-09-30T22:47:08.833539Z","rank":3,"volume":3},{"captured_at":"2026-10-01T00:09:08.327651Z","rank":5,"volume":2},{"captured_at":"2026-10-01T00:09:08.327651Z","rank":4,"volume":3},{"captured_at":"2026-10-01T01:31:08.772054Z","rank":5,"volume":2},{"captured_at":"2026-10-01T01:31:08.772054Z","rank":4,"volume":3},{"captured_at":"2026-10-01T02:53:07.886435Z","rank":5,"volume":2},{"captured_at":"2026-10-01T02:53:07.886435Z","rank":4,"volume":3},{"captured_at":"2026-10-01T04:15:08.210478Z","rank":6,"volume":2},{"captured_at":"2026-10-01T04:15:08.210478Z","rank":5,"volume":3},{"captured_at":"2026-10-01T05:37:48.649158Z","rank":6,"volume":2},{"captured_at":"2026-10-01T05:37:48.649158Z","rank":5,"volume":3}],"posts":[{"platform":"mastodon","url":"https://www.nytimes.com/2026/09/30/science/pancreatic-cancer-drug-daraxonrasib-ben-sasse-resistance.html","author":"nyt_politics@robot.villas","title":null,"snippet":"Clues to Why a Breakthrough Pancreatic Cancer Drug Eventually Stops Working https://www.nytimes.com/2026/09/30/science/pancreatic-cancer-drug-daraxonrasib-ben-sasse-resistance.html # Science # Health # Medicine","posted_at":"2026-09-30T17:39:11Z","likes":2}],"elsewhere":[],"window":"7d"}}