{"ok":true,"trend":{"id":351054,"platform":"news","region":"global","key":"a synthetic lethal drug for microsatellite instability cancers","title":"A synthetic lethal drug for microsatellite instability cancers","url":"https://news.google.com/rss/articles/CBMiX0FVX3lxTE1MVGVTaFlnMm1UWEdCZFZQcVVGNEFJa1hJRmc0MWdsTDhaYWVaN0x4SnUybmVfUHFSMXlGLUNFdjVsOVNLLVRWZFZ4YW9iVi1JMXp4LV8zNU5MT3hfdTFF?oc=5","first_seen":"2026-09-29T11:12:53.304309Z","last_seen":"2026-09-29T12:34:54.901290Z","last_rank":19,"peak_rank":1,"last_volume":null,"peak_volume":0,"seen_count":2,"score":33.85,"category_hint":"medicine","section":"health","category":"medicine","summary":"Researchers have reported the development of a synthetic lethal drug aimed at cancers with microsatellite instability, a genetic feature found in colorectal and other tumor types. Synthetic lethality exploits mutations unique to cancer cells, sparing healthy tissue. The work was published in Nature, and scientists say such drugs could expand treatment options for patients whose tumors resist existing immunotherapies.","why":"A new Nature publication on a promising cancer therapy approach is drawing scientific and medical attention.","tone":"positive","entities":["Nature","microsatellite instability cancers"],"summarized_at":"2026-09-29T11:13:39.368270Z","meta":{"via":"scan","lang":"en","term":"medicine","source":"nature.com","published":"Tue, 29 Sep 2026 09:39:57 GMT"},"nw":null,"promo":null,"kind":null,"importance":null,"hidden":false,"hide_reason":null,"judged_at":null,"title_en":"New synthetic lethal drug targets microsatellite instability cancers","section_name":"Health","category_name":"Medicine","timeline":[{"captured_at":"2026-09-29T11:12:53.304309Z","rank":1,"volume":null},{"captured_at":"2026-09-29T12:34:54.901290Z","rank":19,"volume":null}],"posts":[{"platform":"news","url":"https://news.google.com/rss/articles/CBMiX0FVX3lxTE1MVGVTaFlnMm1UWEdCZFZQcVVGNEFJa1hJRmc0MWdsTDhaYWVaN0x4SnUybmVfUHFSMXlGLUNFdjVsOVNLLVRWZFZ4YW9iVi1JMXp4LV8zNU5MT3hfdTFF?oc=5","author":"Nature","title":"A synthetic lethal drug for microsatellite instability cancers","snippet":null,"posted_at":"2026-09-29T09:39:57Z","likes":null}],"elsewhere":[],"window":"7d"}}