{"ok":true,"trend":{"id":250264,"platform":"news","region":"global","key":"β-silicon effect enables direct hat for enantioconvergent couplings of α-silyl alcohols [image]","title":"β-Silicon effect enables direct HAT for enantioconvergent couplings of α-silyl alcohols [IMAGE]","url":"https://news.google.com/rss/articles/CBMiWEFVX3lxTE9SUlM0b0RFTFJqM3RzOEpOaGVVdWdITGlqWVREWlRLbUk0azNYaHJpX1hEbXh2UlkzMWZoLTV5ekFSMjhMWFREcld6c2V0dUE3SEtuYjhxZjU?oc=5","first_seen":"2026-09-28T15:55:02.223691Z","last_seen":"2026-09-28T20:01:01.406238Z","last_rank":32,"peak_rank":25,"last_volume":null,"peak_volume":0,"seen_count":4,"score":0.7903125,"category_hint":"physics","section":"science","category":"physics","summary":"Chemists report that the beta-silicon effect enables direct hydrogen atom transfer (HAT) for enantioconvergent couplings of alpha-silyl alcohols. The finding means two different alcohol-derived fragments can be joined efficiently into a single enantioenriched product, a long-standing challenge in synthesis, with the silicon atom steering the reaction pathway. Researchers say the approach could simplify how complex chiral molecules, including potential drug candidates, are built from readily available alcohol starting materials.","why":"A new synthetic chemistry method for building chiral molecules from alcohols is of broad interest to pharmaceutical and academic researchers.","tone":"neutral","entities":["alpha-silyl alcohols","hydrogen atom transfer","beta-silicon effect"],"summarized_at":"2026-09-28T21:59:03.543881Z","meta":{"via":"scan","lang":"en","term":"physics","source":"EurekAlert! Science News Releases","generic":0.05,"published":"Mon, 28 Sep 2026 14:23:21 GMT"},"nw":0.37,"promo":0.02,"kind":"news_event","importance":1.23,"hidden":false,"hide_reason":null,"judged_at":"2026-09-28T15:55:15.042569Z","title_en":"Silicon effect enables new route for chiral alcohol couplings","section_name":"Science","category_name":"Physics","timeline":[{"captured_at":"2026-09-28T15:55:02.223691Z","rank":25,"volume":null},{"captured_at":"2026-09-28T17:16:53.778518Z","rank":28,"volume":null},{"captured_at":"2026-09-28T18:38:53.977377Z","rank":30,"volume":null},{"captured_at":"2026-09-28T20:01:01.406238Z","rank":32,"volume":null}],"posts":[{"platform":"news","url":"https://news.google.com/rss/articles/CBMiWEFVX3lxTE9SUlM0b0RFTFJqM3RzOEpOaGVVdWdITGlqWVREWlRLbUk0azNYaHJpX1hEbXh2UlkzMWZoLTV5ekFSMjhMWFREcld6c2V0dUE3SEtuYjhxZjU?oc=5","author":"EurekAlert! Science News Releases","title":"β-Silicon effect enables direct HAT for enantioconvergent couplings of α-silyl alcohols [IMAGE]","snippet":null,"posted_at":"2026-09-28T14:23:21Z","likes":null}],"elsewhere":[],"window":"7d"}}