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- 113-Year-Old Cured of DIPG, the Deadliest Childhood Brain Cancer●A 13-Year-Old Has Been Cured of DIPG, the Deadliest Childhood Brain Cancer
A 13-year-old has reportedly become the first patient cured of DIPG, an aggressive and almost universally fatal childhood brain cancer. The claim, described as a world first, is drawing wide attention because DIPG has resisted decades of treatment efforts, with most children surviving less than a year after diagnosis. Commenters are discussing the significance for pediatric cancer research and what the treatment could mean for future patients.
- 2AstraZeneca invests $2bn in cancer drug partnership with Summit Therapeutics●📈 Astrazeneca invests $2bn in cancer drug tie-up Astrazeneca has invested $2bn in US pharmaceutical firm Summit Therapeu
AstraZeneca has invested $2bn in US biotech firm Summit Therapeutics as part of a major cancer research collaboration. The FTSE 100 drugmaker agreed to buy 109,000 shares in the Nasdaq-listed company at $18.36 per share, funding a tie-up aimed at developing new cancer treatments.
- 3CAR T cell therapy shows two years free of lupus flares●Two years later, CAR T cell therapy shows promise for life without lupus flares
Researchers at UMass Chan Medical School report that lupus patients treated with CAR T cell therapy have remained free of disease flares two years after receiving the one-time cell-based treatment. The therapy, originally developed for blood cancers, reprograms a patient's own immune cells, and the latest follow-up data suggest it may offer lasting remission in autoimmune disease.
- 4p53 found to prevent chromothripsis by balancing transcription and replication▼p53 keeps a transcription–replication balance that prevents chromothripsis
New research reported in Nature shows that the p53 protein, best known as a tumour suppressor, maintains a balance between transcription and DNA replication in cells. When this balance is disrupted, chromosomes can shatter in a catastrophic event known as chromothripsis, a recognised driver of cancer. The findings clarify how p53 guards genome integrity beyond its established roles in halting damaged cells.
- 5Study Finds Proliferative Pause Could Help Prevent Brain Metastasis▼Proliferative Pause Reveals Window to Prevent Brain Metastasis
Researchers report that a 'proliferative pause' — a dormant phase cancer cells enter before spreading — may offer a critical window to intervene and stop brain metastasis before it takes hold. The findings, covered by Inside Precision Medicine, suggest targeting cells during this quiet period could prevent secondary brain tumours, a major cause of death in patients with advanced cancers such as breast cancer and melanoma.
- 6Researchers link cell crowding to optimal treatment timing●Treatment resistance is one of the key challenges in cancer and antibiotic therapy. Researchers led by Dr. Jona Kayser a
Researchers led by Dr. Jona Kayser at MPZPM report that physical processes in dense cell populations strongly influence the best timing of treatment cycles, with implications for both cancer therapy and antibiotics. Treatment resistance remains one of the central challenges in medicine, and the findings suggest that timing could be adjusted based on how tightly cells pack together rather than on biology alone. The work points to new ways of scheduling therapies to delay or avoid resistance.
- 7Reproducibility crisis in biomedical research draws renewed scrutiny▼Reproducibility in biomedical research
Biomedical researchers are once again debating how much of the published scientific literature can be reliably reproduced. Concerns that many experimental findings in fields like cancer biology and pharmacology fail when independently repeated have prompted calls for better study design, data sharing and stricter peer review. The discussion continues to shape how journals, funders and laboratories address the reliability of research that ultimately informs medical practice.
- 8Infections Cause 1 in 8 Cancer Cases Worldwide, Study Finds▼1 in 8 cancer cases worldwide are caused by infections, study finds
A new study has found that infections cause roughly one in eight cancer cases worldwide. The finding points to the significant role viruses and bacteria play in triggering cancers, suggesting prevention through vaccination and treatment of infections could substantially reduce the global cancer burden.
- 9Study reports vitamin C and DMSO shrink skin cancer lesions●A new study reports promising results using vitamin C + DMSO for skin # cancer , including 56% elimination in 12 weeks a
A new study reports that a combination of vitamin C and DMSO produced promising results against skin cancer, with reported elimination of lesions in 56% of cases within 12 weeks and 94% of patients avoiding surgery. Other research suggests DMSO may enhance delivery of anticancer drugs directly into tumors, and early reports involving ivermectin are also circulating.
- 10New synthetic lethal drug targets microsatellite instability cancers▼A synthetic lethal drug for microsatellite instability cancers
Researchers have reported the development of a synthetic lethal drug aimed at cancers with microsatellite instability, a genetic feature found in colorectal and other tumor types. Synthetic lethality exploits mutations unique to cancer cells, sparing healthy tissue. The work was published in Nature, and scientists say such drugs could expand treatment options for patients whose tumors resist existing immunotherapies.
- 11Cancer vaccine puts terminal patient into remission▼Exclusive | She was ready to die. Now she’s in remission — cancer vaccines could be the next big thing in medicine
A woman who had been prepared to die has entered remission after receiving an experimental cancer vaccine, in a report highlighting the technology as a possible next major advance in medicine. The case is being presented as evidence that therapeutic vaccines, which train the immune system to attack tumors, could transform cancer treatment.
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News coverage is highlighting lung cancer cases in people who have never smoked, a group historically overlooked in screening and public awareness. Reports note that never-smokers can develop the disease, often at later diagnosis, and discussion is focusing on possible causes such as air pollution, genetic factors, and radon exposure, as well as what this means for screening guidelines and research funding.
- 13Cancer vaccines emerge as promising new frontier in medicine●She was ready to die. Now she’s in remission — cancer vaccines could be the next big thing in medicine
A terminal cancer patient who had accepted she was dying is now in remission after receiving an experimental cancer vaccine. Doctors say the case highlights the growing potential of personalized cancer vaccines, which train the immune system to attack tumors. The story is fueling optimism that such vaccines could become a major new tool in cancer treatment.