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- 1NFL Week 3 odds: Bills, 49ers, Seahawks, Chiefs favored●Week 3 NFL odds: Bills, 49ers, Seahawks, Chiefs headline biggest favorites
Bookmakers have listed the Buffalo Bills, San Francisco 49ers, Seattle Seahawks and Kansas City Chiefs as the largest favorites on the NFL Week 3 betting slate. The spread-based rundown highlights where oddsmakers see the widest talent gaps this weekend, and bettors and analysts are weighing whether the big favorites can cover as the season's third week gets underway.
- 2NFL Week 3 picks: Broncos over Rams, Bills rout Chargers●NFL Week 3 expert picks, best bets: Broncos upset Rams on 'SNF', Bills rout Chargers
NFL Week 3 delivered surprises: the Denver Broncos upset the Los Angeles Rams on Sunday Night Football, while the Buffalo Bills routed the Los Angeles Chargers. Experts' best bets and predictions for the week drew heavy attention from football fans following the results.